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As a potent ferroptosis inducer and chemotherapeutic drug carrier for AML treatment, Yu et al (169) showed that the ferroptosis-inducing nanomedicine glutathione-capped ferrite nanoparticles successfully overcame AML resistance

Therefore, advancing dermatology-focused clinical trials is essential to define the indications, optimal dosing window, and long-term safety profile of Vitamin D interventions, ultimately supporting evidence-based strategies for skin health management in the aging population (Tables 1 and 2, and 3)

The right objective test should answer a real clinical question

Other strategies target molecules other than NRF2 and GPX4

"During pregnancy, it is recommended to avoid certain skincare products and ingredients due to how they could affect a developing baby," says Dr Solish

Since the approval of the first immunotherapy, interleukin-2 immunotherapy, by the FDA in the late 1990s, 340 immunotherapy, a type of novel cancer therapy taking advantage of the immune system to suppress cancer development, has greatly improved cancer treatment prospects and progressively developed into five subtypes: (i) immune system modulators including various immunomodulatory cytokines, (ii) anticancer vaccines, (iii) ICIs including anti-programmed cell death-1 (anti-PD-1), anti-programmed cell death-ligand 1 (anti-PD-L1) and anti-cytotoxic T-lymphocyte-associated protein-4 (anti-CTLA-4), (iv) T-cell transfer therapy including tumor-infiltrating lymphocyte therapy and CAR-T-cell therapy, and (v) monoclonal antibodies